Single-molecule pull-down for investigating protein-nucleic acid interactions.
Fareh, Mohamed; Loeff, Luuk; Szczepaniak, Malwina; Haagsma, Anna C; Yeom, Kyu-Hyeon; Joo, Chirlmin.
; 105: 99-108, 2016 08 01.
Artigo em Inglês | MEDLINE | ID: mdl-27017911
A retrotransposon-driven dicer isoform directs endogenous small interfering RNA production in mouse oocytes.
Structure of Human DROSHA.
ADAR1 forms a complex with Dicer to promote microRNA processing and RNA-induced gene silencing.
Precursor microRNA-programmed silencing complex assembly pathways in mammals.
Dicer-TRBP complex formation ensures accurate mammalian microRNA biogenesis.
Dicer is dispensable for asymmetric RISC loading in mammals.
Identification of somatic and germ-line DICER1 mutations in pleuropulmonary blastoma, cystic nephroma and rhabdomyosarcoma tumors within a DICER1 syndrome pedigree.
Mutagens interfere with microRNA maturation by inhibiting DICER. An in silico biology analysis.
A phosphate-binding pocket within the platform-PAZ-connector helix cassette of human Dicer.
Two-step cleavage of hairpin RNA with 5' overhangs by human DICER.