High-Specificity Targeted Functional Profiling in Microbial Communities with ShortBRED.
Kaminski, James; Gibson, Molly K; Franzosa, Eric A; Segata, Nicola; Dantas, Gautam; Huttenhower, Curtis.
PLoS Comput Biol
; 11(12): e1004557, 2015 Dec.
Artigo em Inglês | MEDLINE | ID: mdl-26682918
Finding the missing links among metabolites, microbes, and the host.
CRISPR-mediated modular RNA-guided regulation of transcription in eukaryotes.
Structure and Engineering of Francisella novicida Cas9.
PanOCT: automated clustering of orthologs using conserved gene neighborhood for pan-genomic analysis of bacterial strains and closely related species.
Pan-Tetris: an interactive visualisation for Pan-genomes.
Mutant phenotypes for thousands of bacterial genes of unknown function.
Engineering ancestral protein hyperstability.
Adaptive mutations that prevent crosstalk enable the expansion of paralogous signaling protein families.
Sma3s: A universal tool for easy functional annotation of proteomes and transcriptomes.
Metaproteomics analysis reveals the adaptation process for the chicken gut microbiota.