Molecular imprinting as a signal-activation mechanism of the viral RNA sensor RIG-I.
Wu, Bin; Peisley, Alys; Tetrault, David; Li, Zongli; Egelman, Edward H; Magor, Katharine E; Walz, Thomas; Penczek, Pawel A; Hur, Sun.
; 55(4): 511-23, 2014 Aug 21.
Artigo em Inglês | MEDLINE | ID: mdl-25018021
Structural insights into RNA recognition by RIG-I.
Structural basis for dsRNA recognition, filament formation, and antiviral signal activation by MDA5.
Structural basis for ubiquitin-mediated antiviral signal activation by RIG-I.
RIG-I forms signaling-competent filaments in an ATP-dependent, ubiquitin-independent manner.
RIG-I-like receptors: sensing and responding to RNA virus infection.
SLERT Regulates DDX21 Rings Associated with Pol I Transcription.
A DEAD-box RNA helicase promotes thermodynamic equilibration of kinetically trapped RNA structures in vivo.
Structure of Human DROSHA.
PAMPer and tRIGer: ligand-induced activation of RIG-I.
A retrotransposon-driven dicer isoform directs endogenous small interfering RNA production in mouse oocytes.