Circulating precursor CCR7(lo)PD-1(hi) CXCR5âº CD4âº T cells indicate Tfh cell activity and promote antibody responses upon antigen reexposure.
He, Jing; Tsai, Louis M; Leong, Yew Ann; Hu, Xin; Ma, Cindy S; Chevalier, Nina; Sun, Xiaolin; Vandenberg, Kirsten; Rockman, Steve; Ding, Yan; Zhu, Lei; Wei, Wei; Wang, Changqi; Karnowski, Alexander; Belz, Gabrielle T; Ghali, Joanna R; Cook, Matthew C; Riminton, D Sean; Veillette, André; Schwartzberg, Pamela L; Mackay, Fabienne; Brink, Robert; Tangye, Stuart G; Vinuesa, Carola G; Mackay, Charles R; Li, Zhanguo; Yu, Di.
; 39(4): 770-81, 2013 Oct 17.
Artigo em Inglês | MEDLINE | ID: mdl-24138884
Follicular helper CD4 T cells (TFH).
Follicular Helper T Cells.
Human circulating PD-1+CXCR3-CXCR5+ memory Tfh cells are highly functional and correlate with broadly neutralizing HIV antibody responses.
A novel mouse model for tracking the fate of CXCR5-expressing T cells.
Plasticity of Th17 cells in Peyer's patches is responsible for the induction of T cell-dependent IgA responses.
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The transcription factor TCF-1 initiates the differentiation of T(FH) cells during acute viral infection.
The development and fate of follicular helper T cells defined by an IL-21 reporter mouse.