A prevalent C3 mutation in aHUS patients causes a direct C3 convertase gain of function.

Roumenina, Lubka T; Frimat, Marie; Miller, Elizabeth C; Provot, Francois; Dragon-Durey, Marie-Agnes; Bordereau, Pauline; Bigot, Sylvain; Hue, Christophe; Satchell, Simon C; Mathieson, Peter W; Mousson, Christiane; Noel, Christian; Sautes-Fridman, Catherine; Halbwachs-Mecarelli, Lise; Atkinson, John P; Lionet, Arnaud; Fremeaux-Bacchi, Veronique.
Blood; 119(18): 4182-91, 2012 May 03.
Artigo em Inglês | MEDLINE | ID: mdl-22246034