Latent class model with familial dependence to address heterogeneity in complex diseases: adapting the approach to family-based association studies.
Bureau, Alexandre; Croteau, Jordie; Tayeb, Arafat; Mérette, Chantal; Labbe, Aurélie.
; 35(3): 182-9, 2011 Apr.
Artigo em Inglês | MEDLINE | ID: mdl-21308764
Power consequences of linkage disequilibrium variation between populations.
Sampling GWAS subjects from risk populations.
On optimal pooling designs to identify rare variants through massive resequencing.
Sample size requirements to detect gene-environment interactions in genome-wide association studies.
Estimation of odds ratios of genetic variants for the secondary phenotypes associated with primary diseases.
Quantifying and correcting for the winner's curse in quantitative-trait association studies.
Validity and power of association testing in family-based sampling designs: evidence for and against the common wisdom.
Dissecting the genetics of complex traits using summary association statistics.
Multiple testing corrections for imputed SNPs.
Phenotype harmonization and cross-study collaboration in GWAS consortia: the GENEVA experience.