Bradykinin B2 Receptors of dendritic cells, acting as sensors of kinins proteolytically released by Trypanosoma cruzi, are critical for the development of protective type-1 responses.
Monteiro, Ana Carolina; Schmitz, Verônica; Morrot, Alexandre; de Arruda, Luciana Barros; Nagajyothi, Fnu; Granato, Alessandra; Pesquero, João B; Müller-Esterl, Werner; Tanowitz, Herbert B; Scharfstein, Julio.
; 3(11): e185, 2007 Nov.
Artigo em Inglês | MEDLINE | ID: mdl-18052532
Bradykinin B2 and dopamine D2 receptors form a functional dimer.
The role of N-terminal and C-terminal Arg residues from BK on interaction with kinin B2 receptor.
Kinin danger signals proteolytically released by gingipain induce Fimbriae-specific IFN-gamma- and IL-17-producing T cells in mice infected intramucosally with Porphyromonas gingivalis.
Gangliosides and chondroitin sulfate desensitize and internalize B2 bradykinin receptors.
Pro-angiogenic effect of human kallikrein-related peptidase 12 (KLK12) in lung endothelial cells does not depend on kinin-mediated activation of B2 receptor.
Bradykinin promotes the chemotactic invasion of primary brain tumors.
Expression and localization of recombinant human B2 receptors in the methylotrophic yeast Pichia pastoris.
Kinin-B2 receptor activity determines the differentiation fate of neural stem cells.
The kinin B1 receptor regulates muscle-specific E3 ligases expression and is involved in skeletal muscle mass control.
Tissue kallikrein is essential for invasive capacity of circulating proangiogenic cells.