Functional validation of the anaplastic lymphoma kinase signature identifies CEBPB and BCL2A1 as critical target genes.
Piva, Roberto; Pellegrino, Elisa; Mattioli, Michela; Agnelli, Luca; Lombardi, Luigia; Boccalatte, Francesco; Costa, Giulia; Ruggeri, Bruce A; Cheng, Mangeng; Chiarle, Roberto; Palestro, Giorgio; Neri, Antonino; Inghirami, Giorgio.
J Clin Invest
; 116(12): 3171-82, 2006 Dec.
Artigo em Inglês | MEDLINE | ID: mdl-17111047
Structural basis for the recognition of c-Src by its inactivator Csk.
Phosphorylation of the adaptor ASC acts as a molecular switch that controls the formation of speck-like aggregates and inflammasome activity.
The crystal structure of pseudokinase PEAK1 (Sugen kinase 269) reveals an unusual catalytic cleft and a novel mode of kinase fold dimerization.
Targeting the SH2-kinase interface in Bcr-Abl inhibits leukemogenesis.
A secreted tyrosine kinase acts in the extracellular environment.
Spatial and Temporal Regulation of Receptor Tyrosine Kinase Activation and Intracellular Signal Transduction.
Self-regulation of exopolysaccharide production in Bacillus subtilis by a tyrosine kinase.
REQUIREMENT OF THE TEC FAMILY TYROSINE KINASE BTK29A FOR COURTSHIP MEMORY IN Drosophila MALES.
Phosphorylation Impacts N-end Rule Degradation of the Proteolytically Activated Form of BMX Kinase.
Discovering the first tyrosine kinase.