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¿Tienen los corticoides inhalatorios un rol en la bronquiolitis? / ¿Tienen los corticoides inhalatorios un rol en la bronquiolitis? / Do inhaled corticosteroids have a role for bronchiolitis?

Alarcón-Andrade, Gonzalo; Cifuentes, Lorena.
Medwave; 18(2): e7183, 2018 Apr 17.
Artigo em Espanhol, Inglês | MEDLINE | Abr 2018 | ID: mdl-29677180
Resumo: INTRODUCTION: Bronchiolitis consists of an acute small airways inflammation secondary to a viral infection and is a frequent pathology among children under 2 years. The use of inhaled corticosteroids during bronchiolitis has been proposed to reduce recurrent wheeze or asthma, however there is controversy about it. METHODS: To answer this question we used Epistemonikos, the largest database of systematic reviews in health, which is maintained by screening multiple information sources, including MEDLINE, EMBASE, Cochrane, among others. We extracted data from the systematic reviews, reanalyzed data of primary studies, conducted a meta-analysis and generated a summary of findings table using the GRADE approach. RESULTS AND CONCLUSIONS: We identified three systematic reviews including 11 randomized trials. We concluded that inhaled corticosteroids do not reduce recurrent wheeze or asthma in patients with bronchiolitis.